IV Individualized dosing.
Induction of anaesth Adult Titrate approx 20-40 mg every 10 sec.
<55 yr 1.5-2.5 mg/kg.
Patient of ASA grades III & IV Approx 20 mg every 10 sec.
Maintenance of anaesth Adult 4-12 mg/kg/hr using continuous infusion. Less stressful surgical procedures (eg, minimal invasive surgery): Approx 4 mg/kg/hr as continuous infusion.
Elderly, patient in unstable general conditions or hypovolaemic; ASA grades III & IV 4 mg/kg/hr; increments of 25-50 mg using repeat bolus inj.
General anaesth Childn >8 yr Induction: approx 2.5 mg/kg,
1 mth-3 yr 2.5-4 mg/kg.
Sedation for diagnostic & surgical procedures Adult 0.5-1 mg/kg over 1-5 min for onset of sedation.