Pharmaniaga Aciclovir Tablet Dosage & Drug Information

Concise Prescribing Info

Contents

Aciclovir

Indications/Uses

Treatment & prophylaxis of herpes genitalis, treatment of herpes zoster, herpes simples & varicella (chickenpox).

Dosage/Direction for Use

Adult Genital herpes infections Initially 200 mg 4 hrly 5 times daily for 10 days. Recurrent infections Intermittent therapy: 200 mg 4 hrly 5 times daily for 5 days. Chronic suppressive therapy: 400 mg bd or 200 mg 3-5 times daily. Herpes zoster infections 800 mg 5 times daily for 7 days. Varicella infections 20 mg/kg up to 800 mg/dose 5 times daily for 7 days. Childn Varicella infections 20 mg/kg qds. Max: 800 mg, >6 yr 800 mg qds, 2-5 yr 400 mg qds, <2 yr 200 mg qds.

Administration

May be taken with or without food: May be taken w/ meals to reduce GI discomfort.

Contraindications

Pregnancy.

Special Precautions

High doses. Immunocompromised & geriatric patients. Renal impairment. Lactation.

Adverse Reactions

Fever, headache, pain, peripheral oedema, rarely anaphylaxis. Confusion, dizziness, hallucinations, paraesthesia, somnolence, GI disturbances, leucopenia, lymphadenopathy, myalgia, alopecia, pruritus, rash, urticaria, visual abnormalities.

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Drug Interactions

Concomitant use w/ nephrotoxic medications, probenecid.

MIMS Class

Antivirals

ATC Classification

J05AB01 - aciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.

Regulatory Classification

Presentation/Packing

Form

Pharmaniaga Aciclovir Tablet tab 200 mg

Packing/Price

5 × 10's

Form

Pharmaniaga Aciclovir Tablet tab 400 mg

Packing/Price

5 × 10's

Pharmaniaga Aciclovir Tablet

aciclovir

Manufacturer:

Pharmaniaga Manufacturing Berhad

Distributor:

Pharmaniaga Logistics