Mosapride: Uses, Dosage, Side Effects and More

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Disorders associated with reduced gastrointestinal motility

Adult: As anhydrous citrate: 5 mg tid.

Special Precautions

Continuous admin of this drug is not recommended if no improvement in GI symptoms is observed after 2 wk of admin. Elderly, renal impairment, hepatic impairment.

Adverse Reactions

Diarrhoea, abdominal pain; dizziness; constipation; headache; insomnia; nausea.

Drug Interactions

Mosapride concentration increased by erythromycin. May increase risk of QT prolongation with QT prolonging drugs.

Action

Description:
Mechanism of Action: Mosapride is a 5-HT₄ receptor agonist which increases the release of acetylcholine and stimulates GI motility. It also has 5-HT₃ antagonist properties.

MIMS Class

GIT Regulators, Antiflatulents & Anti-Inflammatories

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