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Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

22 Oct 2025 by

Treatment with the Janus kinase (JAK) 1 inhibitor povorcitinib results in significant repigmentation of the body and face in adult patients with extensive nonsegmental vitiligo (NSV), with an acceptable safety profile, through 52 weeks, reports a phase II study.

Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

22 Oct 2025

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

22 Oct 2025 by

In the phase III C-POST trial, adjuvant cemiplimab prolongs disease-free survival (DFS) in individuals at high risk for recurrence of cutaneous squamous cell carcinoma (cSCC).

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

22 Oct 2025

Ensitrelvir a viable alternative to available antivirals for COVID-19

21 Oct 2025 by

The investigational oral antiviral ensitrelvir shows potent antiviral activity in COVID-19, although its effect is slightly weaker than that of ritonavir-boosted nirmatrelvir, according to the ongoing, phase II, randomized controlled, adaptive pharmacometric platform PLATCOV trial.

Ensitrelvir a viable alternative to available antivirals for COVID-19

21 Oct 2025

Early IL-17 inhibitor use tied to quick response in psoriasis

21 Oct 2025

Early treatment with interleukin (IL)-17 inhibitors accelerates response and fosters disease modification in patients with psoriasis, reveals a study.

Early IL-17 inhibitor use tied to quick response in psoriasis

21 Oct 2025

Budesonide–formoterol reliever combo superior to salbutamol alone for mild asthma in kids

20 Oct 2025

The combination of inhaled corticosteroid budesonide plus formoterol appears to work better than the short-acting β2-agonist (SABA) salbutamol alone as reliever monotherapy for mild asthma in children, being associated with lower incidence of asthma attacks in a randomized controlled trial (RCT).

Budesonide–formoterol reliever combo superior to salbutamol alone for mild asthma in kids

20 Oct 2025

Trimetazidine lowers risk of stroke in presence of both IHD and AF

20 Oct 2025 by

Treatment with the antianginal agent trimetazidine appears to protect against the incidence of stroke and its recurrence in patients with both ischaemic heart disease (IHD) and atrial fibrillation (AF), as shown in a study from Hong Kong.

Trimetazidine lowers risk of stroke in presence of both IHD and AF

20 Oct 2025

Ceftriaxone 1 vs 2 g: Which dose leads to fewer clinical failure in bacteremia?

20 Oct 2025

The incidence of clinical failure does not differ between 1- and 2-g doses of ceftriaxone for the treatment of bacteremia, results of a study have shown.

Ceftriaxone 1 vs 2 g: Which dose leads to fewer clinical failure in bacteremia?

20 Oct 2025

Early check-in protocol improves adherence to anticancer medications

20 Oct 2025

The implementation of an early check-in protocol may enable pharmacists of health-system specialty pharmacies (HSSPs) to enhance patient adherence to oral anticancer medication (OAM), suggests a recent study.

Early check-in protocol improves adherence to anticancer medications

20 Oct 2025

Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

17 Oct 2025 by

A shorter acetylcysteine regimen shows similar safety and effectiveness to the standard regimen for moderate paracetamol overdoses ≤30 g, reveals a recent study. This almost halves the duration of treatment required.

Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

17 Oct 2025

COVID-19 vaccines remain effective against severe outcomes

17 Oct 2025 by

Even as COVID-19 severity wanes and public uptake declines, previous receipt of the 2024-2025 COVID vaccines continues to reduce emergency visits, hospital stays, and deaths among US veterans, as shown in a recent study.

COVID-19 vaccines remain effective against severe outcomes

17 Oct 2025

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Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

Ensitrelvir a viable alternative to available antivirals for COVID-19

Ensitrelvir a viable alternative to available antivirals for COVID-19

Early IL-17 inhibitor use tied to quick response in psoriasis

Early IL-17 inhibitor use tied to quick response in psoriasis

Budesonide–formoterol reliever combo superior to salbutamol alone for mild asthma in kids

Budesonide–formoterol reliever combo superior to salbutamol alone for mild asthma in kids

Trimetazidine lowers risk of stroke in presence of both IHD and AF

Trimetazidine lowers risk of stroke in presence of both IHD and AF

Ceftriaxone 1 vs 2 g: Which dose leads to fewer clinical failure in bacteremia?

Ceftriaxone 1 vs 2 g: Which dose leads to fewer clinical failure in bacteremia?

Early check-in protocol improves adherence to anticancer medications

Early check-in protocol improves adherence to anticancer medications

Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

COVID-19 vaccines remain effective against severe outcomes

COVID-19 vaccines remain effective against severe outcomes