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Treatment of advanced thromboangiitis obliterans (Buerger's disease) with critical limb ischemia in cases where revascularization is not indicated.
Treatment of patients with severe peripheral arterial occlusive disease (PAOD), particularly those at risk of amputation and in whom surgery or angioplasty is not possible.
Treatment of patients with severe disabling Raynaud's phenomenon unresponsive to other therapies.
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